revolve1
revolve2
revolve3
revolve4
spacer
spacer



Allergy show


Tesco


FFE


ads home page 1


Foodcycle


Fria


ads home page 8


ESPGHAN diagnostic criteria work well in selected population

Recent research by a group at La Fe University Hospital in Valencia in Spain has validated the new ESPGHAN diagnostic criteria discussed by Alex Gazzola earlier this year here on CoeliacsMatter.

The researchers performed a retrospective review of all patients suspicious of having CD who had undergone a small bowel biopsy in our Gastroenterology Unit. 150 patients met the inclusion criteria and were enrolled in the study. 116 were positive for the TT: 113/116 (97.4%) had a Marsh 2/3 histological lesion and had been considered to have CD. Thus PPV of the TT was 97.4%.

The other three cases (2.6%) had Marsh 0/1 lesion, so were considered false positives for the TT. However, on follow up, all three children developed histological damage after a gluten challenge.

Finally, PPV of the TT was 100%. 34 patients were negative for the TT: 22 patients are celiac, 3 are celiac but challenge gluten diet is pending, and the 9 patients left have other gastrointestinal disorder.

They concluded that the study supported the view that in selected children who are symptomatic and positive for the Triple Test, CD diagnosis could be established independently of histological findings.

J Pediatr Gastroenterol Nutr. 2012 Oct 29.
Coeliac Disease: The New Proposed ESPGHAN Diagnostic Criteria Do Work Well in A Selected Population.

 

 

Click here for more research on coeliac disease

 

 

Top of page

stumbleupon twitter About facebook digg
twitter spacer facebook

Click here for NEW FreeFrom Events CALENDAR


Click here to subscribe to our FREE E-NEWSLETTER
Click here to see a recent issue


Click here for our BLOG


Click here for recent
ARTICLES & RESEARCH
on CoeliacsMatter


Click here gluten-free
COOKERY COURSES



The cost of gluten-free bread.
Lucinda Bruce-Gardyne, founder of Genius Gluten Free, explains why gluten-free bread genuinely does cost a lot more to make than 'normal' supermarket bread.



Coeliac Disease and Gluten Sensitivity: A Clinical Perspective.

Study day run by The Academy for Paediatric Gastroenterology and Coeliac UK.
Alex Gazzola reports.


All about Marmite...
Sue Cane investigates whether the
love-it-or-hate-it spread really
is suitable for coeliacs – or not ...


Gluten Summit – the overview
Micki Rose pulls together the findings
of the 2014 Gluten Summit.